姓名: 楊佳寧 Chia-Ning Yang
職稱:

副教授

學歷: 國立中山大學 化學系 學士
美國凱斯西儲大學 化學系 博士
經歷: Department of Chemistry, Carnegie Mellon University 博士後研究員
行政院原子能委員會 輻射偵測中心放射化學組 約聘工程師
中山醫學大學 應用化學系 助理教授
義守大學 影像暨放射技術學系 助理教授
國立高雄大學 生物科技研究所 助理教授
辦公室: 理學院大樓 328
實驗室:

分子模擬暨藥物設計實驗室理學院大樓 326 室)

聯絡電話:

886-7-5919717,校內分機7717,7356

E-Mail:

cnyang@nuk.edu.tw

學術專長: 生化電腦演算設計
蛋白質作用力辨識
電腦輔助藥物設計

開授課程:

(大學部) 普通化學微積分分析化學計算機概論
(研究所) 專題研究專題討論

研究計劃:

1. 計畫名稱:利用 DNA Computing 解決一地圖著色問題(1/2)
計畫編號:NSC 91-2119-M-040-001 
執行期間:December 2002 – July 2003
參與工作:計畫主持人

2. 計畫名稱:利用 DNA Computing 解決一地圖著色問題(2/2)
計畫編號:NSC 92-2113-M-214-002 
執行期間:August 2003 – July 2004
參與工作:計畫主持人

3. 計畫名稱:利用兩種DNA Computing方法解決一SAT問題
計畫編號:NSC 93-2113-M-214-001 
執行期間:August 2004 - July 2005
參與工作:計畫主持人

4. 計畫名稱:利用DNA Computing所設計之半加法器及全加法器
計畫編號:NSC 94-2113-M-214-002 
執行期間:August 2005 - July 2006
參與工作:計畫主持人

5. 計畫名稱:兩種以DNA分子為基礎的分子級裝置之設計:狀態轉換器及邏輯閘
計畫編號:NSC 95-2113-M-214-002 
執行期間:August 2006 –July 2007
參與工作:計畫主持人

6. 計畫名稱:利用分子模擬計算和生化實驗探討Pin1 WW domain和五種peptide的交互作用
計畫編號:NSC 96-2113-M-390-005 ()
執行期間:August 2007 –July 2008
參與工作:計畫主持人

7. 計畫名稱:夫喃(furo)﹝2,3-b﹞奎林類(guinolines)(CIL-102及其衍生物)之合成與抗癌活性評估(Ⅰ)(Ⅱ)
計畫編號:(96-2323-B-037-001-) 
執行期間:August 2007 –July 2010
參與工作:計畫共同主持人

8. 計畫名稱:蛋白質結構分類與全原子預測
執行期間:2008
參與工作:計畫共同主持人

9. 計畫名稱:CIL-102及其衍生物 TCH-1227, TCH-1259及其衍生物之優化及抗癌研究
執行期間:2009
參與工作:計畫共同主持人

10. 計畫名稱:硝基柫喃乙烯(HZY-2023)及其衍生物的合成與抗癌活性評估-硝基喃乙烯(HZY-2023)及其衍生物作為抗癌候選藥物於細胞與實驗動物之分析
計畫單位:國科會
計畫編號:(99-2320-B-037-013-MY3)
執行期間:August 2010 –July 2013
參與工作:計畫共同主持人
11. 計畫名稱:利用電腦模擬藥物篩選平台解析中草藥之表現特徵來發展其生物仿製藥物
計畫單位:經濟部
執行期間:October 2010 –September 2013
參與工作:分項計畫主持人
12. 計畫名稱:以電腦輔助理論計算開發新穎HIV反轉錄酶抑制劑
計畫單位:國科會(大專生專題)
計畫編號:( 101-2815-C-390-026-B)
執行期間:July 2012 –February 2013
參與工作:指導教授
13. 計畫名稱:利用等溫滴定微量熱法及分子動態模擬研究第一類型和第四類型WW domain之蛋白交互作用及比較其辨認機制
計畫單位:國科會
計畫編號:(101-2320-B-390-001-)
執行期間:August 2012 –July 2013
參與工作:主持人

14. 計畫名稱:利用DNA分子設計四種分子裝置:一個半加法器,兩個半減法器,及一個檢

測單核甘酸多態性分析片段分析探針

計畫單位:國科會

計畫編號:(NSC 102-2113-M-390 -007 -MY2)

執行期間:August 2013-July 2015

參與工作:主持人

15. 計畫名稱:以電腦輔助理論計算開發新穎p38αMAPK抑制劑

計畫單位:國科會(大專生專題)

計畫編號:(NSC102-2815-C-390-023-B)

執行期間:July 2013 –February 2014

參與工作:指導教授

 

期刊論文:

1.  Bursulaya, B. D.; Jeon, J.; Yang, C.N.; Zichi, D. A.; Kim, H.J.

(1999) "A Truncated Adiabatic Basis-Set Approach to Solvent Electronic Structure Variations.” Simulation and Theory of Electrostatic Interactions in Solution, pp. 281-300.

 

2.  Yang, C.N.; Klippenstein, S.J.

(1999) "Theory and Modeling of the Binding in Cationic Transition-Metal- Benzene Complexes” J. Phys. Chem. A, 103 (8), pp. 1094-1103. (SCI)

 

3.  Ryzhov, V.; Yang, C.N.; Klippenstein, S.J.; Dunbar, R.C.

(2000) "Binding Energies of Chromium Cations with Fluorobenzenes from Radiactive Association Kinetics”. International Journal of Mass Spectrometry and Ion Processes, 185/186/187, 913-923.

 

4. Yang,C.N.; Kim, H.J.

(2000) "Dielectric Relaxation of Hot Water”, J. Chem. Phys. 113(15), pp. 6025-6028.

 

5.  Bursulaya, B.D.; Jeon, J.; Yang, C.N.; Kim, H.J.

(2000) "On the Photoabsorption Spectroscopy of Water”. J. Phys. Chem. A, 104 (1), pp. 45-52. (SCI)

 

6.  Gapeev, Alexei; Yang, C.N.; Klippenstein, Stephen J.; Dunbar, Robert C.  

(2000) "Binding Energies of Gas-Phase Metal Ions with Pyrrole: Experimental and Quantum Chemical Results”. J. Phys. Chem. A, 104 (14), pp. 3246-3256.

 

7.  Stephen J. Klippenstein.; Yang, C.N.

(2000) "Density Functional Theory Predictions for the Binding of Transition Metal Cations to π systems: from Acetylene to Coronene and Tribenzocyclyne”.  International Journal of Mass Spectrometry 201, 253–267.

 

8.  Yang, C.N.*(corresponding); Yang, C.B.

(2005) "DNA Solution of SAT Problem by a Modified Sticker Model”, BioSystems, 81, pp1-9. (NSC-91-2213-E-110-022)

 

9.  Lin, C.H.; Cheng, S.P.; Yang, C.N.*(corresponding); Yang, C.B.

(2007) "Solving Satisfiability Problems Using a Novel Microarray-based DNA Computer”. BioSystems, 90, pp242-252. (NSC-91-2213-E-110-022)

 

10. Tseng, C.H., Chen, Y.L.; Lu, P.J.; Yang, C.N.; Tzeng, C.C.

(2008) "Synthesis and Antiproliferative Evaluation of Certain Indeno﹝1,2-c﹞quinoline Derivatives”, Bioorganic & Medicinal Chemistry 16, 3153-3162.

 

11. Chen, Y.L.; Lin, H.C.; Yang, C.N.; Lu, P.J.; Tzeng, C.C.

(2008) "Synthesis and Antiproliferative Evaluation of 4-Anilino-nmethoxyfuro﹝2,3-b﹞quinoline Derivatives (n = 6, 7)Part 5. Chemistry & Biodiversity, 5, 2667-2670.

 

12. Yang, C.N.; Huang, K.S.; Yang, C.B.; Hsu, C.Y.

(2009) "Error-Tolerant Minimum Finding with DNA Computing.” The International Journal of Innovative Computing, Information and Control. 5, 10(A), 3045-3057.

 

13. Chang, C.Y.; Liau, H.H.; Lu, P.J.; Chen, H.L.; Yang, C.N.; Shaw, A.Y.

(2009) "Synthesis of 2-Styrylchromones as a Novel Class of Antiproliferative Agents Targeting Carcinoma Cells.” European Journal of Medicinal Chemistry, 44, 6, 2552-2562.

 

14. Chen, H.L.; Chang, C.Y.; Lee, H.T.; Lin, H.H.; Lu, H.H.; Lu, P.J.; Yang, C.N.; Shiau, C.W.; Shaw, A.Y.

(2009) "Synthesis and Pharmacological Exploitation of Clioquinol-Derived Copper-Binding Apoptosis Inducers Triggering Reactive Oxygen Species Generation and MAPK Pathway Activation .” Bioorganic & Medicinal Chemistry, 17, 7239-7247.

 

15. Howng, S.L.; Hwang, C.C.; Hsu, C.Y.; Hsu, M.Y.; Teng C.Y.; Chou C.H.; Lee, M.F.; Wu, C.H.; Chiou, S.J.; Lieu, A.S.; Loh, J.K.; Yang, C.N.; Lin, C.S.; Hong, Y.R.*

(2010) "Involvement of the Residues of GSKIP, AxinGID, and FRATtide in Their Binding with GSK3β to Unravel a Novel C-terminal Scaffold-binding Region.” Molecular Cell Biochemistry, 339 (1-2): 23-33.

 

16. Shaw, A.Y.; Chang, C.Y.; Hsu, M.Y.; Lu, P.J.; Yang,C.N.; Chen, H.L.; Lo, C.W.; Shiau, C.W.; Chern, M.K.

(2010) "Synthesis and structure-activity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents.”European Journal of Medicinal Chemistry, 45, 2860-2867.

 

17. Shaw, A.Y.; Liau, H.H.; Lu, P.J.; Lee, C.H.; Yang,C.N.;Chen, J.Y.; Xu, Z.

(2010) "3,5-Diaryl-1H-pyrazole as a molecular scaffold for the synthesis of apoptosisinducing agents.”Bioorganic & Medicinal Chemistry, 18, 9, 3270-327.

 

18. Lu, C. M.; Chen, Y. L.; Chen, H.L.; Chen, C. A.; Lu, P. J.; Yang, C. N.; Tzeng, C.C.

(2010) "Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives.”Bioorganic & Medicinal Chemistry, 18, 1948-1957.

 

19. Tseng, C.H.; Tzeng, C.C.; Yang, C.L.; Lu, P.J.; Chen, H.L.; Li, H.Y.; Chuang, Y.C.; Yang, C.N.* (co-corresponding); Chen, Y.L.*

(2010) "Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2" J. Med. Chem, 53, 6164-6179.

 

20. Hong, C.J.; Tsai, P. J.; Cheng, C.Y.; Chou, C.K.; Jheng, H. F.; Chuang, Y.C.; Yang, C.N.; Lin, Y.T.; Hsu, C.W.; Cheng, I.H.; Chen, S. Y.; Tsai, S.J.; Liou, Y. J.; Tsai, Y.S.

(2010) "ENU Mutagenesis Identifies Mice with Morbid Obesity and Severe Hyperinsulinemia Caused by a Novel Mutation in Leptin."PLos ONE, 5, 12, e15333.

 

21.Tang, X.N.; Lo, C.W.; Chuang, Y.C.; Chen, C.T.; Sun, Y.C.; Hong, Y.R.; Yang, C.N.*(corresponding)

(2011) "Prediction of the binding mode between GSK3ß and a peptide derived from GSKIP using molecular dynamics simulation." Biopolymers, 95, 7, 461-471. (Impact factor 2012: 2.879)

22.Chen, Y.W.; Chen, Y.L.; Tseng, C.H.; Liang, C.C.; Yang, C.N.; Yao, Y.C.; Lu, P.J.; Tzeng, C.C.

(2011) "Discovery of 4-Anilinofuro[2,3-b]quinoline Derivatives as Selective and Orally Active Compounds Against Non-small Cell Lung Cancers." Journal of Medicinal Chemistry, 54, 4446–4461. (Impact factor 2012: 5.614)

 

23.Chia-Ning Yang*(corresponding), Chun-Yu Hsu, Yu-Chung Chuang

(2012) "Molecular Beacon-Based Half Adder and Half Subtractor"Chemical Communications, 48, 112-114. (Impact factor 2012: 6.378)

 

24. Hsiu-Yu Wang, Liang-I Juo, Yuh-Te Lin, Michael Hsiao, Jen-Tai Lin, Chen-Hsun Tsai, Yu-Hao Tzeng, Yu-Chung Chuang, Nan-Shan Chang, Chia-Ning Yang* (co-corresponding), Pei-Jung Lu*
(2012) “WW Domain-Containing Oxidoreductase Promotes Neuronal Differentiation via Negative Regulation of Glycogen Synthase Kinase 3β” Accepted by Cell Death and Differentiation, 19(6):1049-59. (Impact factor 2012: 8.371)

 

25. Chih-Hua Tseng, Cherng-Chyi Tzeng, Pin-Keng Shih, Chia-Ning Yang, You-Chung Chuang, Shin-I Peng, Chang-Sheng Lin, Jih-Pyang Wang, Chih-Mei Cheng, Yeh-Long Chen*
(2012)“Identification of furo[3, 2:3,4]naphtho[1,2-d]imidazole derivatives as orally active and selective inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1)” Molecular Diversity, 16(2):215-229. (Impact factor: 2.861)

 

26. Da-Sheng Wang, Po-Chen Chu, Chia-Ning Yang, Ribai Yan, Yu-Chung Chuang, Samuel Kulp, Ching-Shih Chen.
(2012) "Development of a Novel Class of Glucose Transporter Inhibitors", Journal of Medicinal Chemistry, 55, 38273836. (Impact factor 2012: 5.614)

 

27. Chen Lin, Pei-Jung Lu, Chia-Ning Yang, Christopher Hulme, Arthur Y. Shaw*
(2012) "Structure-activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells." Medicinal Chemistry Research, 22, 5, 2385-2394. (Impact factor 2012: 1.612)

 

28. Chi-Tai Yeh, Alexander T H Wu, Peter M H Chang, Kuan-Yu Chen, Chia-Ning Yang, Shuenn-Chen Yang, Chao-Chi Ho, Chun-Chi Chen, Yu-Lun Kuo, Pei-Ying Lee, Yu-Wen Liu, Chueh-Chuan Yen, Michael Hsiao, Pei-Jung Lu, Jin-Mei Lai, Liang-Shun Wang, Chih-Hsiung Wu, Jeng-Fong Chiou, Pan-Chyr Yang, and Chi-Ying F. Huang
(2012) Trifluoperazine, an Antipsychotic Agent, Inhibits Cancer Stem Cell Growth and Overcomes Drug Resistance of Lung Cancer. American Journal of Respiratory and Critical Care Medicine,186 (11):1180-8.(Impact factor 2011: 11.041)

 

29. Yu-Peng Liu, Hui-Ling Chen, Cherng-Chyi Tzeng,* Pei-Jung Lu, Yu-Cheng Li, Chih-Hua Tseng, Yeh-Long Chen, and Chia-Ning Yang* (co-corresponding)
(2013) TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells. Breast Cancer Research and Treatment, 138 (2):383-393. (Impact factor 2012: 4.469)

 

30. Ying-Hsin Chang, Jun-Yan Chen, Chiou-Yi Hor, Yu-Chung Chuang, Chang-Biau Yang, Chia-Ning Yang* (corresponding)
(2013) Computational Study of Estrogen Receptor-alpha Antagonist with Three-Dimensional Quantitative Structure-Activity Relationship, Support Vector Regression, and Linear Regression Methods, International Journal of Medicinal Chemistry, Volume 2013,  Article ID 743139, 13 pages.

31. Hsin-Wen Chang, Fu-Sheng Chung, Chia-Ning Yang* (corresponding)
(2013) Molecular modeling of p38 alpha MAPK inhibitors through 3D-QSAR and molecular dynamics simulations. Journal of Chemical Information and Modeling, 53(7):1775-1786. (Impact factor 2012: 4.304)

32. Chia-Ning Yang* (corresponding), Yi-Li Chen, Hung-Yin Lin, Chun-Yu Hsu
(2013) An Optical Deoxyribonucleic Acid-based Half-subtractor. Chemical Communications, 49(78):8860-2. (Impact factor 2012: 6.378)

33. Chih-Hua Tseng, Cherng-Chyi Tzeng, Chiao-Li Yang, Pei-Jung Lu, Yu-Peng Liu, Hui-Ling Chen, Chien-Yu Chen, Chia-Ning Yang* (co-corresponding), and Yeh-Long Chen*
(2013) Discovery of indeno[1,2-c]quinoline derivatives as dual topoisomerases I/II inhibitors: Part 3, Molecular Diversity, 17:781-799. (Impact factor 2012: 2.861)

34. Shi-Yie Cheng, Neng-Lang Shih, Kuang-Yu Hou, Mang-Jye Ger, Chia-Ning Yang, Shang-Kewi Wang, Chang-Yih Duh.*

(2014) Kelsoenethiol and dikelsoenyl ether, two unique kelsoane-type sesquiterpenes, from the

Formosan soft coral Nephthea erecta. Bioorganic & Medicinal Chemistry Letters 24, 473–475.

 

35. Shi-Yie Cheng a,b, Neng-Lang Shih a, Cheng-Ta Chuang b, Shu-Fen Chiou b, Chia-Ning Yang a,Shang-Kwei Wang c, Chang-Yih Duh.*

(2014) Sinugyrosanolide A, an unprecedented C-4 norcembranoid, from the Formosan soft

coral Sinularia gyrosa. Bioorganic & Medicinal Chemistry Letters 24, 1562–1564.

 

36. Ru-Wei Lin, Chia-Ning Yang, ShengYu Ku, Cheng-Jung Ho, Shih-Bo Huang, Min-Chi Yang, Hsin-Wen Chang, Chun-Mao Lin, Jaulang Hwang, Yeh-Long Chen, Cherg-Chyi Tzeng,* Chihuei Wang*
(2014) CFS-1686 causes cell cycle arrest at intra-S phase by interference of interaction of topoisomerase 1 with DNA
PLoS ONE 9(12): e113832

 

37. Yu-Chung Chuang, Ching-Hsun Chang, Jen-Tai Linand Chia-Ning Yang* (Corresponding)
(2015) Molecular modelling studies on SIRT2 inhibitors using 3D-QSAR and molecular dynamics simulations
Molecular Biosystems, 11, 723 - 733 (Impact Factor 2013: 3.183)
*The front cover of Molecular Biosystems Issue 3, 2015 presents our work.

38. Cheng-Han Lin, Hao-Yi Li, Yu-Cheng Lee, Marcus J Calkins, Kuen-Haur Lee, Chia-Ning Yang (co-corresponding), * Pei-Jung Lu*
(2015) Landscape of Pin1 in cell cycle.
Experimental Biology and Medicine 2015 Feb 7 pii: 1535370215570829 (Impact Factor 2013: 2.223)紙本檔頁碼240: 403408  

 

39. Ribai Yan, Hsiao-Ching Chuang, Naval Kapuriya, Chih-Chien Chou, Po-Ting Lai, Hsin-Wen Chang, Chia-Ning Yang, Samuel Kulp, Ching-Shih Chen
(2015) Exploitation of the Ability of γ-Tocopherol to Facilitate Membrane Co-localization of Akt and PHLPP1 to Develop PHLPP1-Targeted Akt Inhibitors
Accepted by Journal of Medicinal Chemistry, February 2015

 

40. Hung-Yin Lin, Jian-Zhou Chen, Hao-Yi Li, Chia-Ning Yang* (corresponding)

(2015) A simple three-input DNA-based system works as a full-subtractor Accepted by Scientific Reports on April 21, 2015 (Impact Factor 2013: 5.078)

 

41. Chih-Hua Tseng, Cherng-Chyi Tzeng, Chih-Yao Hsu, Chih-Mei Cheng, Chia-Ning Yang, Yeh-Long Chen
(2015) Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers
European Journal of Medicinal Chemistry 97 (2015) 306e319

 

42. I-Chung Cheng, Ya-Chun Chen, Chia-Wei Ku, Yu-Wen Huang, Chia-Ning Yang* (corresponding).
(2015) Structural and Dynamic Characterization on Mutated Keap1 for Varied Affinity toward Nrf2: A Molecular Dynamics Simulation Study. Accepted by Journal of Chemical Information and Modeling (Impact Factor 2014: 3.738), Sep 8 2015.

 

43. Ya-Jyun Chen, Chia-Ning Yang* (corresponding)
(2016) Molecular Modeling of Structural and Functional Variance in the SAGA Deubiquitinating Module Caused by Sgf73 Y57A Mutation
Accepted by RSC Advances on 2016/6/29 (Impact factor 2015: 3.289)

 

研討會論文:

1. 楊佳寧, 鄭筱萍, 林哲信
(2004) “A Microarray Assisted DNA Computing on SAT Problems.”中國化學年會,台中中興大學,November 20-21

 

2. 鄭筱萍, 林哲信, 楊昌彪, 楊佳寧
(2005) “Solutions to SAT Problems by Modified Sticker Model and Microarray Assisted DNA Computing.”台灣生物資訊年會,成功大學醫學院, August 8-10. (獲得壁報論文競賽第一名)

 

3. Hsu, C.Y.; Yang, C.B.; Huang, K.S.; Yang, C.N.
(2005) ”Minimum Finding with DNA Computing.” 數位生活與網際網路科技研討會,成功大學資訊系所.

 

4.Huang, Y.Y.; Yang, C.B.; Tseng, K.T.; Yang, C.N.
(2005) “Protein Folding Prediction with Genetic Algorithms.” In Proc. of the 4th Conference on Information Technology and Applications in Outlying Islands,pp.130-139,澎湖.

 

5.Yang, C.N.; Hsu, C.Y.; Yang, C.B.; Huang, K.S.
(2006) “Error-Tolerant Minimum Finding with DNA Computing, the 12th international meeting on DNA computing.” Seoul, Korea.

 

6.Cheng, H.P.; Lin, C.H.; Yang, C.B.; Yang, C.N.
(2006) “Solutions to SAT Problems by Modified Sticker Model and Microarray Assisted DNA Computing.” The 12th DNA computing conference, Seoul, Korea, June, 2006.

 

7.Yang, C.N.; Huang, Y.L.; Lu, P.J.
(2006) “VGHKS-698v Interacts with Microtubule Organization and Causes Mitotic Arrest Followed by Apoptosis in Hela Cells.” 20th IUBMB International Congress of Biochemistry and Molecular Biology, Kyoto, Japan, June, 2006.

 

8.Yang, C.N.; Chao, C.H.; Cheng, H.P.; Lin, C.H.
(2006) “A MEMS Based DNA Computer for Solving SAT Problems.” Proceedings of the 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems. 172-177, Zhuhai, China.

 

9.Chang, T.Y.; Lin, C.H.; Yang, C.N.; Lin, C.W.
(2007) “A Hyper-Step DNA Computing System Based On Surface Plasmon Resonance.” Proceeding of SPIE, Vol. 6465, 646505, 1-10.

 

10. 楊佳寧, 黃郁文, 郭勁宏
(2009) “A Molecular Dynamics Study in Determining the Pin1 WW-Pintide Complex.”中國化學年會,Dec 5-6. 高雄縣義守大學.

 

11. 楊佳寧, 盧怡如, 李豪嶧
(2009) “A Molecular Dynamics Study on the Role of Phosphoserine-proline Motif in Pin1 WW-CTD Complex.”中國化學年會,Dec 5-6. 高雄縣義守大學.

 

12. 陳俊諺, 楊佳寧, 莊祐仲
(2009) “A 3D-QSAR Study on Arylbenzothiophene Derivatives for MCF-7 Cell Inhibitory Activity and Relative Binding Affinity with Respect to E2 on ERα."中國化學年會,Dec 5-6高雄縣義守大學.

 

13. 楊佳寧, 羅振維, 莊祐仲
(2009) “A Molecular Dynamics Study of GSK3β-GSKIP and GSK3β-WWOX2 Complexes.”中國化學年會,Dec 5-6高雄縣義守大學.

 

14. 莊祐仲, 楊佳寧
(2009) ”A Ligand-based CoMSIA Study on a Series of Furo[3',2':3,4]naphtho[1,2-d]imidazole Analogs.” 中國化學年會,Dec 5-6. 高雄縣義守大學.

 

15. (2011) Ying-Hsin Chang, Jun-Yan Chen, Chiou-Yi Hor, Yu-Chung Chuang, Chang-Biau

Yang,Chia-Ning Yang.“Computational study of estrogen receptor-alpha antagonist with three-
dimensional quantitative structure-activity relationship, support vector regression, and linear

regression methods”, Global Breast Cancer Conference, Seoul, Korea.

 

16. (2011) 楊佳寧,許純瑜,莊祐仲. Molecular beacon-based half adder and half subtractor.中國化學

年會,清華大學.

 

17. (2011) Chia-Ning Yang, Yu-Peng Liu, Pei-Jung Lu. ”MicroRNA18 down-regulated STK4

expression and promoted cell proliferation in prostate cancer cells”, Sixteenth Annual Meeting of

the RNA society, Kyoto, Japan.

 

18. (2012) Liu, Yu-Peng, Yang, Chia-Ning Yang, Lu, Pei-Jung. “Cisplatin enriches drug resistant

CD133 positive cells via activation of NOTCH signaling in non-small cell lung cancer”,

International Society for Stem Cell Research, Yokohama, Japan.

 

19. (2012) 楊佳寧.”以DNA分子信標所組成之半減法器進行邏輯運算”.中國化學年會,成功大

學.

 

20. (2013) Chia-Ning Yang, Yu-Peng Liu, Pei-Jung Lu. “Mst1 down regulation promotes tumor

invasion/migration and is associated with poor prognosis in human colon cancer”, American

Association of Cancer Research Annual Meeting 2013, Washington, D.C., USA.

 

21. (2013) Chia-Ning Yang, Yu-Peng Liu, Pei-Jung Lu. “Novel small compounds targeting cancer

stem cells of non-small cell lung cancer”, International Association for the Study of Lung Cancer

and 15th World Conference on Lung Cancer, Sydney, Australia.

 

22. (2014) Chia-Ning Yang, Ya-Jyun Chen. Molecular dynamics study on Keap1 point mutations in

lung cancer, American Association for Cancer Research Annual Meeting 2014, San Diego, USA.

 

23. (2014) 楊佳寧,張景勛*. A Molecular Dynamics Study on Grb7 SH2 Domain.化學年會,工研院,新竹. (2014/11/21~23)


24. (2014) 楊佳寧,莊祐仲*,張景勛. A study on SIRT2 inhibitors using 3D-QSAR and molecular dynamics simulations.化學年會,工研院,新竹. (2014/11/21~23)


25. (2014) 楊佳寧,陳雅君*. Structural and dynamic characterization on mutated Keap1: a molecular dynamics simulation study.化學年會,工研院,新竹. (2014/11/21~23)


26. (2014) 楊佳寧*,林宏殷,陳建州. A Molecular Beacon-Based Full-Subtractor.化學年會,工研院,新竹. (2014/11/21~23)

 

27. (2015) 陳雅君,楊佳寧. Molecular Modeling Studies of the SAGA Deubiquitinating Module Structural and Functional Variance Caused by Sgf73/Y57A. 2015年理論計算化學小組九月研討會,台灣大學化學系,台北. (2015/9/8)

 

邀請演講:

1."DNA Computing" ,第二十屆生物夏令營,台中東海大學,Aug 18-20, 2004.
2."A Novel Microarray-based DNA Computer for Solving SAT Problems Utilizing a Modified Sticker Model", The 2nd International Meeting on Microsensors and Microsystems, January 17, 2006, 成功大學 。

3. "Structural and Dynamic Characterization on Mutated Keap1 for Varied Affinity toward Nrf2",第六屆海峽兩岸理論與計算化學會議,國立中正大學,2015/1/27。

4. "Molecular modeling studies of SIRT2 inhibitors",2015年/有機藥物研討會,國立高雄師範大學化學系,2015/5/7。

特殊榮譽:

鄭筱萍,林哲信, 楊昌彪, 楊佳寧
(2005)‘Solutions to SAT Problems by Modified Sticker Model and Microarray Assisted DNA Computing’. Bioinformatics in Taiwan, 成功大學, Dec 5-6. 壁報論文競賽第一名.

科技部103年度補助大專院校獎勵特殊優秀人才 (103年8月~104年7月)

科技部104年度補助大專院校獎勵特殊優秀人才 (104年8月~105年7月)